薑黃素 <br> 為何是濕疹的潛在剋星 <br> 減癢去紅腫、抗炎、抗過敏

Eczema and dermatitis are common skin conditions characterized by symptoms such as dryness, redness, itching, and inflammation. The causes can be infections, allergies, immune system dysfunction, stress, and more. There is no specific cure for these skin problems, and many people seek various methods to alleviate eczema symptoms, including traditional medical treatments such as steroids, immunosuppressants, and topical creams. Most patients only experience limited relief, and these preparations often come with different side effects. Eczema requires long-term and patient treatment, sometimes taking several years.
In recent years, curcumin has garnered attention as a natural anti-inflammatory and antioxidant. Here, we explore the benefits of curcumin for eczema sufferers, discuss its effects on eczema, and its potential therapeutic effects.

Anti-inflammatory action:
Curcumin contains an active ingredient called "curcuminoid" that possesses powerful anti-inflammatory properties. Studies have confirmed its anti-inflammatory and anti-allergic effects, as curcumin can inhibit the release of inflammatory mediators and alleviate skin inflammation. This anti-inflammatory action helps reduce skin redness and control itching and rash symptoms in eczema patients, and curcumin also exhibits anti-infection properties.

Antioxidant action:
The worsening of eczema is associated with oxidative stress and free radical damage. Curcumin has potent antioxidant capabilities, neutralizing free radicals and reducing oxidative stress on the skin. This antioxidant action may help alleviate eczema symptoms, promote skin repair, and regeneration.

Immune modulation:

Curcumin is believed to have immunomodulatory effects. Eczema is a disease caused by immune system dysregulation, and curcumin may alleviate eczema symptoms by modulating immune responses. Research has shown that curcumin can regulate immune cell activity, reduce inflammatory responses, thereby alleviating skin inflammation and discomfort caused by eczema.

Skin protection:

Curcumin has skin-protective abilities. It enhances the skin's barrier function, reduces moisture loss, and maintains skin health. This is particularly important for eczema patients as their skin is often prone to dryness and damage. Therefore, maintaining clean and moisturized skin is an essential measure for relieving eczema symptoms.

Conclusion:

Curcumin, as a natural anti-inflammatory and antioxidant, may have potential benefits for the treatment of eczema. Its anti-inflammatory, antioxidant, immune modulation, and skin protection actions may help alleviate eczema symptoms and promote skin repair and health. However, curcumin is poorly soluble and difficult for the body to absorb, with an absorption rate of only about 5-6%. Therefore, when choosing curcumin supplements, it is necessary to select high-quality curcumin with a purity of over 90% and use good absorption enhancers to maximize its effectiveness. Currently, the most effective bioenhancers for improving curcumin absorption (bioavailability) are Phenylcapsaicin piperine compounds. Experimental evidence has shown that Phenylcapsaicin can increase curcumin absorption by more than 6 times and is currently the most efficient bioenhancer available. Phenylcapsaicin has been registered in the European Union (EFSA) and has received FDA/GRAS certification in the United States. It is also known as aXivite, a registered trademark of a Swedish company, aXichem AB.

It is important to note that turmeric powder is different from curcumin. Turmeric powder is used for coloring and flavoring in cooking and does not have significant health benefits.
https://pubmed.ncbi.nlm.nih.gov/29065496/
https://pubmed.ncbi.nlm.nih.gov/32713186/

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